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Custom Oligonucleotide Synthesis

Oligonucleotides available in Germany only

  • DNA- and RNA oligonucleotides
  • More than 150 fluorescent labels and 40 modifications
  • High coupling efficiencies
  • Also synthesis of very long oligonucleotides or synthesis of large quantities
  • Fast delivery times

DNA oligonucleotides

DNA oligonucleotides are offered in different synthesis quantities and different purification grades. The products are dissolved in sterile water and adjusted to a concentration of 0.1 nmol/µl. For all synthesis setup fees and shipping costs are already included.

Modifications

For oligonucleotides a wide range of modifications is available. More than 150 different color labels can be offered. Moreover 5'-modifications by non-nucleoside components such as amino, thio-linker or phosphates, 3'-modifications or internal modifications by nucleoside components can be provided. All modifications of oligonucleotides are inclusive a 2 fold HPLC purification (1x for synthesis, 1x after coupling of the modification) at no extra charge.

RNA oligonucleotides

For the synthesis of long RNAs, labeled RNAs, 2‘- and base modified RNAs, triphosphates, modified dinucleotides and dsRNAs a variety of new synthesis methods were developed to ensure a high yield and biological activity to the RNA oligonucleotides. As a consequence high-quality synthesis products, especially also long RNA molecules can be are offered, which are further more protected against degradation by nucleases.

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